Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Lung, Epithelial Cell
DISEASE(S): Coronavirus Infectious Disease
SUBMITTER: Raja Sekhar Nirujogi
LAB HEAD: Yogesh Kulathu
PROVIDER: PXD022904 | Pride | 2021-09-15
REPOSITORIES: pride
Action | DRS | |||
---|---|---|---|---|
Nsp3_PhosphoSTYSites.txt | Txt | |||
Nsp3_evidence.txt | Txt | |||
Nsp3_parameters.txt | Txt | |||
Nsp3_peptides.txt | Txt | |||
Nsp3_proteinGroups.txt | Txt |
Items per page: 1 - 5 of 10 |
PloS one 20210716 7
Of the 16 non-structural proteins (Nsps) encoded by SARS CoV-2, Nsp3 is the largest and plays important roles in the viral life cycle. Being a large, multidomain, transmembrane protein, Nsp3 has been the most challenging Nsp to characterize. Encoded within Nsp3 is the papain-like protease domain (PLpro) that cleaves not only the viral polypeptide but also K48-linked polyubiquitin and the ubiquitin-like modifier, ISG15, from host cell proteins. We here compare the interactors of PLpro and Nsp3 an ...[more]