Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
SUBMITTER: Lei Lu
LAB HEAD: Lei Lu
PROVIDER: PXD022941 | Pride | 2022-06-09
REPOSITORIES: Pride
Items per page: 5 1 - 5 of 32 |
Lu Lei L Scalf Mark M Shortreed Michael R MR Smith Lloyd M LM
Journal of the American Society for Mass Spectrometry 20210323 6
Top-down proteomics is a key mass spectrometry-based technology for comprehensive analysis of proteoforms. Proteoforms exhibit multiple high charge states and isotopic forms in full MS scans. The dissociation behavior of proteoforms in different charge states and subjected to different collision energies is highly variable. The current widely employed data-dependent acquisition (DDA) method selects a narrow <i>m</i>/<i>z</i> range (corresponding to a single proteoform charge state) for dissociat ...[more]