Proteomics

Dataset Information

0

Gas plasma combined with antibiotics for the eradication of methicillin-resistant Staphylococcus aureus biofilm


ABSTRACT: Gas plasma treatment caused polymerization of the SaClpP proteins and loss of protein function due to the oxidative modifications induced by reactive oxygen species of the gas plasma.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Staphylococcus Aureus (strain Col)

SUBMITTER: Li Guo  

LAB HEAD: Dingxin Liu

PROVIDER: PXD023352 | Pride | 2021-09-09

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
CA.raw Raw
CB.raw Raw
ClpP_seq.txt Txt
F000744.mgf Mgf
F000744.mzid.gz Mzid
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Publications

Cold Atmospheric-Pressure Plasma Caused Protein Damage in Methicillin-Resistant <i>Staphylococcus aureus</i> Cells in Biofilms.

Guo Li L   Yang Lu L   Qi Yu Y   Niyazi Gulimire G   Huang Lingling L   Gou Lu L   Wang Zifeng Z   Zhang Lei L   Liu Dingxin D   Wang Xiaohua X   Chen Hailan H   Kong Michael G MG  

Microorganisms 20210517 5


Biofilms formed by multidrug-resistant bacteria are a major cause of hospital-acquired infections. Cold atmospheric-pressure plasma (CAP) is attractive for sterilization, especially to disrupt biofilms formed by multidrug-resistant bacteria. However, the underlying molecular mechanism is not clear. In this study, CAP effectively reduced the living cells in the biofilms formed by methicillin-resistant <i>Staphylococcus aureus</i>, and 6 min treatment with CAP reduced the <i>S. aureus</i> cells in  ...[more]

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