Dataset Information

Method development and characterization of the low molecular weight peptidome of human wound fluids

ABSTRACT: Peptidomic analysis and methodological development of characterization of low molecular weight peptidome of human wound fluids and plasma.Data on wound fluid peptides is also found in PXD023244

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

SUBMITTER: sven kjellstrom

LAB HEAD: Sven Kjellström

PROVIDER: PXD023884 | Pride | 2021-09-10

REPOSITORIES: Pride

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Method development and characterisation of the low-molecular-weight peptidome of human wound fluids.

van der Plas Mariena Ja MJ Cai Jun J Petrlova Jitka J Saleh Karim K Kjellström Sven S Schmidtchen Artur A

eLife 20210706

The normal wound healing process is characterised by proteolytic events, whereas infection results in dysfunctional activations by endogenous and bacterial proteases. Peptides, downstream reporters of these proteolytic actions, could therefore serve as a promising tool for diagnosis of wounds. Using mass-spectrometry analyses, we here for the first time characterise the peptidome of human wound fluids. Sterile post-surgical wound fluids were found to contain a high degree of peptides in comparis ...[more]

PMID: 34227939

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			Action	DRS
	peptides_sample_1.xlsx	Xlsx
	peptides_sample_2.xlsx	Xlsx
	peptides_sample_3.xlsx	Xlsx
	sample1_1.raw	Raw
	sample1_2.raw	Raw