Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Wei Xie
LAB HEAD: Jun Zhou
PROVIDER: PXD023906 | Pride | 2021-09-10
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
QD2020-19459-2.raw | Raw | |||
Table_S1.zip | Other |
Items per page: 1 - 2 of 2 |
The Journal of biological chemistry 20210101
Exposure of mucosal epithelial cells to the human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp120 is known to disrupt epithelial cell junctions by impairing stathmin-mediated microtubule depolymerization. However, the pathological significance of this process and its underlying molecular mechanism remain unclear. Here we show that treatment of epithelial cells with pseudotyped HIV-1 viral particles or recombinant gp120 protein results in the activation of protein kinase G 1 (PK ...[more]