Proteomics

Dataset Information

0

MiR-146 modulation in ALS astrocytes


ABSTRACT: Regarding astrocytes and microglia, we are looking for pathways related with inflammatory activation, phagocytosis and vesicular/exosome trafficking. Regarding motor neurons, we are searching for pathways related with mitochondrial dynamics, Endoplasmic Reticulum stress, cell death, axonal transport, synaptic vesicles transport and oxidative stress. The general aim is to identify putative hits in ALS that relates with miR-146a expression.

INSTRUMENT(S): Orbitrap Fusion Lumos, Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Spinal Cord Motor Neuron, Astrocyte Of The Cerebral Cortex, Cell Culture, Microglial Cell

DISEASE(S): Amyotrophic Lateral Sclerosis

SUBMITTER: Frank Stein  

LAB HEAD: Dora Brites

PROVIDER: PXD024294 | Pride | 2021-04-06

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
F100521.dat Other
F100522.dat Other
F100525.dat Other
F100527.dat Other
F100529.dat Other
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