Proteomics

Dataset Information

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Fibroblast growth factor 2 promotes bladder hypertrophy caused by partial bladder outlet obstruction


ABSTRACT: The current study aims to investigate molecular alterations and biomarkers associated with partial BOO (PBOO) in rats.TMT-Labeling Proteomic Analysis of PBOO Bladder Tissues at Week 5.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Bladder

DISEASE(S): Bladder Neck Obstruction

SUBMITTER: Zhenxing Yang  

LAB HEAD: Zhenxing Yang

PROVIDER: PXD024378 | Pride | 2021-09-10

REPOSITORIES: Pride

Dataset's files

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Action DRS
S9733TQ_1.raw Raw
S9733TQ_10.raw Raw
S9733TQ_11.raw Raw
S9733TQ_12.raw Raw
S9733TQ_13.raw Raw
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Publications

Fibroblast Growth Factor 2 Promotes Bladder Hypertrophy Caused by Partial Bladder Outlet Obstruction.

Gao Ye Y   Liu Peilin P   He Fan F   Yang Xingliang X   Wu Ronghua R   Chen Wei W   Li Longkun L   Yang Zhenxing Z  

Frontiers in cell and developmental biology 20210330


Non-invasive biomarkers to identify patients with bladder outlet obstruction (BOO)-related dysfunction are still needed to guide clinical practice. The current study aims to investigate molecular alterations and biomarkers associated with partial BOO (PBOO) in rats. Sprague-Dawley rats were used to establish the BOO model. Serum samples from 60 patients with benign prostatic hyperplasia (BPH) were used for enzyme-linked immunosorbent assay analysis. RNA sequencing and TMT-labeling proteomic anal  ...[more]

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