Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF, Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Kidney
DISEASE(S): Renal Clear Cell Carcinoma
SUBMITTER: Aydanur Senturk
LAB HEAD: Nurhan Ozlu
PROVIDER: PXD024696 | Pride | 2021-11-02
REPOSITORIES: Pride
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Molecular cancer research : MCR 20210511 8
Clear cell renal cell carcinoma (ccRCC) is the third most common and most malignant urological cancer, with a 5-year survival rate of 10% for patients with advanced tumors. Here, we identified 10,160 unique proteins by in-depth quantitative proteomics, of which 955 proteins were significantly regulated between tumor and normal adjacent tissues. We verified four putatively secreted biomarker candidates, namely, PLOD2, FERMT3, SPARC, and SIRPα, as highly expressed proteins that are not affected by ...[more]