Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos, LTQ Orbitrap Velos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Bronchoalveolar Lavage
DISEASE(S): Idiopathic Pulmonary Fibrosis
SUBMITTER: Enxhi Shaba
LAB HEAD: Prof. Luca Bini
PROVIDER: PXD025590 | Pride | 2021-08-06
REPOSITORIES: pride
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FA09-20_Lane_12_1-4_Lumos.raw | Raw | |||
FA09-20_Lane_14_1-4.raw | Raw | |||
FA09-20_Lane_14_1-4_Lumos.raw | Raw | |||
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International journal of molecular sciences 20210527 11
In the longtime challenge of identifying specific, easily detectable and reliable biomarkers of IPF, BALF proteomics is providing interesting new insights into its pathogenesis. To the best of our knowledge, the present study is the first shotgun proteomic investigation of EVs isolated from BALF of IPF patients. Our main aim was to characterize the proteome of the vesicular component of BALF and to explore its individual impact on the pathogenesis of IPF. To this purpose, ultracentrifugation was ...[more]