Dataset Information

APP infected and healthy pig BALF iTRAQ-LC-MS/MS

ABSTRACT: Porcine pleuropneumonia caused by Actinobacilluspleuropneumoniae (APP) is a swine respiratory disease with an important impact around the world either as a single infection or part of the porcine respiratory disease complex. The data of interaction between hosts and pathogens has becoming more crucial for exploration of the mechanism. However, up to now, comparatively little information is available on the systemic and dynamic changes that occur in pig BALF in response to APP infection. This study used iTRAQ to identify differentially expressed proteins (DEPs) in pig BALF in response to APP infection.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Bronchoalveolar Lavage

SUBMITTER: Zhu Rining

LAB HEAD: Lei Liancheng

PROVIDER: PXD026983 | Pride | 2022-02-17

REPOSITORIES: pride

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Dataset's files

Source:

			Action	DRS
	BALF-labelfree.rar	Other
	Report-BALF.rar	Other

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Publications

Dynamic immune response characteristics of piglets infected with Actinobacillus pleuropneumoniae through omic.

Zhu Rining R Jiang Hexiang H Wang Jun J Bao Chuntong C Liu Haiyao H Li Fengyang F Lei Liancheng L

AMB Express 20211224 1

Porcine infectious pleuropneumonia is characterized by a high-rate of carriage and mixed infection with other pathogens. The host immune response induced by Actinobacillus pleuropneumoniae (APP) is the basis for elucidating pathogenesis and controlling disease. However, there is currently no comprehensive and dynamic data characterising the host immune response. In this study, piglets were infected with APP and differentially expressed proteins of bronchoalveolar lavage fluid (BALF) and peripher ...[more]

PMID: 34952961

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