Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Christian Frese
LAB HEAD: Christian Karl Frese
PROVIDER: PXD025702 | Pride | 2023-11-23
REPOSITORIES: Pride
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QE1_191113_19M031_.msf | Msf | |||
QE1_191113_19M031_1_1.raw | Raw | |||
QE1_191113_19M031_1_2.raw | Raw | |||
QE1_191113_19M031_1_3.raw | Raw | |||
QE1_191113_19M031_1_4.raw | Raw |
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Journal of leukocyte biology 20240101 2
Staphylococcus aureus strains that produce the toxin Panton-Valentine leukocidin (PVL-SA) frequently cause recurrent skin and soft tissue infections. PVL binds to and kills human neutrophils, resulting in the formation of neutrophil extracellular traps (NETs), but the pathomechanism has not been extensively studied. Furthermore, it is unclear why some individuals colonized with PVL-SA experience recurring infections whereas others are asymptomatic. We thus aimed to (1) investigate how PVL exerts ...[more]