Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: GSE122195
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture, Neutrophil
SUBMITTER: Raghothama Chaerkady
LAB HEAD: Sonja Hess
PROVIDER: PXD012176 | Pride | 2019-04-26
REPOSITORIES: Pride
Items per page: 1 - 5 of 26 |
The Journal of clinical investigation 20190415 5
Diabetic individuals are at considerable risk for invasive infection by Staphylococcus aureus, however, the mechanisms underlying this enhanced susceptibility to infection are unclear. We observed increased mortality following i.v. S. aureus infection in diabetic mice compared with nondiabetic controls, correlating with increased numbers of low-density neutrophils (LDNs) and neutrophil extracellular traps (NETs). LDNs have been implicated in the inflammatory pathology of diseases such as lupus, ...[more]