Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive Plus
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Brown Adipose Tissue, White Adipose Tissue
SUBMITTER: Giovanni Renzone
LAB HEAD: Andrea Scaloni
PROVIDER: PXD026080 | Pride | 2022-05-20
REPOSITORIES: Pride
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EVs_Aquilano_2021_1_20211015182750.raw | Raw | |||
EVs_Aquilano_2021_1_20211016164346.raw | Raw | |||
EVs_Aquilano_2021_1_20211018195626.raw | Raw |
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Cell metabolism 20220318 4
Recent findings have demonstrated that mitochondria can be transferred between cells to control metabolic homeostasis. Although the mitochondria of brown adipocytes comprise a large component of the cell volume and undergo reorganization to sustain thermogenesis, it remains unclear whether an intercellular mitochondrial transfer occurs in brown adipose tissue (BAT) and regulates adaptive thermogenesis. Herein, we demonstrated that thermogenically stressed brown adipocytes release extracellular v ...[more]