Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Plasma
SUBMITTER: Jean ARMENGAUD
LAB HEAD: Jean Armengaud
PROVIDER: PXD026189 | Pride | 2024-05-02
REPOSITORIES: Pride
Action | DRS | |||
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F215666.dat | Other | |||
F215666_p0.05.mzid.gz | Mzid | |||
F215667.dat | Other | |||
F215667_p0.05.mzid.gz | Mzid | |||
F215668.dat | Other |
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Biomolecules 20240321 3
This study aims at identifying molecular biomarkers differentiating responders and non-responders to treatment with Tumor Necrosis Factor inhibitors (TNFi) among patients with axial spondyloarthritis (axSpA). Whole blood mRNA and plasma proteins were measured in a cohort of biologic-naïve axSpA patients (<i>n</i> = 35), pre and post (14 weeks) TNFi treatment with adalimumab. Differential expression analysis was used to identify the most enriched pathways and in predictive models to distinguish r ...[more]