Dataset Information

Proteomic Identification of Lung Adenocarcinoma and Normal Lung Tissue

ABSTRACT: To identify proteomic of lung adenocarcinoma, we collected five pairs of lung adenocarcinoma and normal lung tissues from the clinic for analysis

INSTRUMENT(S): timsTOF Pro

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung

DISEASE(S): Lung Adenocarcinoma

SUBMITTER: Xu Ran

LAB HEAD: Zhang linyou

PROVIDER: PXD027008 | Pride | 2022-01-12

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	Proteomics_txt.zip	Other
	cancer_13_Slot2-14_1_9944.d.rar	Other
	cancer_16_Slot2-15_1_9945.d.rar	Other
	cancer_3_Slot2-11_1_9941.d.rar	Other
	cancer_7_Slot2-12_1_9942.d.rar	Other

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Publications

Identification of ubiquitinated substrate proteins and their gene expression patterns in lung adenocarcinoma.

Xu Ran R Lu Tong T Zhao Jiaying J Li Qi Q Wang Jun J Peng Bo B Liu Jian J Zhang Pengfei P Qu Lidong L Chang Xiaoyan X Yao Lingqi L Zhang Linyou L

Annals of translational medicine 20211101 22

<h4>Background</h4>Lung cancer is a malignant disease with the highest cancer-related mortality rate. In lung adenocarcinoma (LUAD), protein ubiquitination can regulate multiple biological processes. A LUAD ubiquitylome analysis has not yet been reported.<h4>Methods</h4>We used for the first time ion mobility into liquid chromatography-mass spectrometry to perform accurate and reliable ubiquitylome and proteomic analysis of clinical LUAD and normal tissues and combined it with transcriptome data ...[more]

PMID: 34988201

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