Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Cervix Carcinoma
SUBMITTER: Zhi-Hui Deng
LAB HEAD: Zhi-Hui Deng
PROVIDER: PXD027166 | Pride | 2022-08-12
REPOSITORIES: pride
Action | DRS | |||
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BPI_16383_xibaohe_itraq_1-8-uniprot-human.msf | Msf | |||
BPI_16383_xibaohe_itraq_1.raw | Raw | |||
BPI_16383_xibaohe_itraq_10.raw | Raw | |||
BPI_16383_xibaohe_itraq_11.raw | Raw | |||
BPI_16383_xibaohe_itraq_12.raw | Raw |
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Hong Xian X Wang Tao T Du Juan J Hong Yu Y Yang Cai-Ping CP Xiao Wei W Li Yang Y Wang Ming M Sun He H Deng Zhi-Hui ZH
Scientific reports 20220611 1
Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that regulates endosomal trafficking in eukaryotic cells. Recent studies have shown that VPS35 promotes tumor cell proliferation and affects the nuclear accumulation of its interacting partner. In this study, isobaric tags for relative and absolute quantitation (iTRAQ)-based mass spectrometry were used to measure the changes in nuclear protein abundance in VPS35-depleted HeLa cells. A total of 47 differentially expr ...[more]