Dataset Information
Cell aggregate FA and hFLO MS/MS
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Fibroblast
DISEASE(S): Disease Free
SUBMITTER: 
Jonard Valdoz
LAB HEAD: Pam M. Van Ry
PROVIDER: PXD027296 | Pride | 2022-10-14
REPOSITORIES: Pride
Dataset's files
Items per page: 1 - 5 of 7 |
Publications
Soluble ECM promotes organotypic formation in lung alveolar model.
Biomaterials 20220316
Micropatterned suspension culture creates consistently sized and shaped cell aggregates but has not produced organotypic structures from stable cells, thus restricting its use in accurate disease modeling. Here, we show that organotypic structure is achieved in hybrid suspension culture via supplementation of soluble extracellular matrix (ECM). We created a viable lung organoid from epithelial, endothelial, and fibroblast human stable cell lines in suspension culture. We demonstrate the importan ...[more]
