Proteomics

Dataset Information

0

ZNF555 interaction partners in humans rhabdomyosarcoma cells


ABSTRACT: CoIP-MS/MS experiments to identify interacting proteins for human ZNF555 in muscle cancer rhabdomyosarcoma cells TE671.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Rhabdomyosarcoma Cell Line

DISEASE(S): Rhabdomyosarcoma

SUBMITTER: Iryna PIROZHKOVA  

LAB HEAD: Vasily Ogryzko

PROVIDER: PXD027542 | Pride | 2024-01-03

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
RMS_Ctl1.msf Msf
RMS_Ctl1.raw Raw
RMS_Ctl2.msf Msf
RMS_Ctl2.raw Raw
RMS_Ctl3.msf Msf
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Publications


We have recently identified the uncharacterized ZNF555 protein as a component of a productive complex involved in the morbid function of the 4qA locus in facioscapulohumeral dystrophy. Subsequently named DiPRO1 (Death, Differentiation, and PROliferation related PROtein 1), our study provides substantial evidence of its role in the differentiation and proliferation of human myoblasts. DiPRO1 operates through the regulatory binding regions of SIX1, a master regulator of myogenesis. Its relevance e  ...[more]

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