Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Colon
SUBMITTER: yaqin zhang
LAB HEAD: Di Wang
PROVIDER: PXD027745 | Pride | 2022-05-20
REPOSITORIES: pride
Action | DRS | |||
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CTRL2.raw | Raw | |||
Evodiamine_treated.raw | Raw | |||
Model2.raw | Raw | |||
parameters.txt | Txt | |||
peptides.txt | Txt |
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Zhang Yongfeng Y Zhang Yaqin Y Zhao Yang Y Wu Wanyue W Meng Weiqi W Zhou Yulin Y Qiu Ye Y Li Chenliang C
Molecular medicine reports 20220401 5
Evodiamine (Evo) is an alkaloid that can be extracted from the berry fruit <i>Evodia rutaecarpa</i> and has been reported to exert various pharmacological effects, such as antidiarrheal, antiemetic and antiulcer effects. <i>In vivo</i>, the potential effects of Evo were investigated in a mouse model of dextran sodium sulfate (DSS)‑induced ulcerative colitis (UC) and in adenomatous polyposis coli (Apc)<sup>MinC</sup>/Gpt C57BL/6 mice with colorectal cancer (CRC), where the latter harbours a point ...[more]