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Radiation tolerance mechanism of Deinococcus radiodurans using lable-free proteomics

ABSTRACT: Even though these results have shown several key proteins played an import role in radiation tolerance mechanism of DR, they were lack of the deep protein coverage, global protein analysis as well as the dynamic changes of DR, which limits further understanding of biological changes in response to ionizing radiation. To the best of our knowledge, the global and specific radiation tolerance mechanism of DR has not been elucidated yet. Therefore, a label-free quantitative proteomics was applied to conduct a systematic and comprehensive proteomic analysis on DR after 6 kGy γ-irradiation at different time point. Differentially abundant proteins (DAPs) with a fold-change cutoff were reported. These proteins, providing a deep understanding of the molecular response to ionizing radiation.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Deinococcus Radiodurans

SUBMITTER: Shuchen Xin

LAB HEAD: Zhang yongqian

PROVIDER: PXD027969 | Pride | 2022-08-29

REPOSITORIES: Pride

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			Action	DRS
	DR_C_0h_1.raw	Raw
	DR_C_0h_3.raw	Raw
	DR_C_0h_4.raw	Raw
	DR_C_12h_3.raw	Raw
	DR_C_12h_4.raw	Raw

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