Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Eric Bonneil
LAB HEAD: Sylvain Meloche
PROVIDER: PXD028061 | Pride | 2023-02-21
REPOSITORIES: Pride
Action | DRS | |||
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ERK3_phospho_cytosol_ID1_HCD.raw | Raw | |||
ERK3_phospho_cytosol_ID2_HCD.raw | Raw | |||
ERK3_phospho_cytosol_ID3_HCD.raw | Raw | |||
ERK3_phospho_cytosol_ID4_HCD.raw | Raw | |||
ERK3_phospho_nuclei_ID1_HCD.raw | Raw |
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Journal of cellular physiology 20221228 3
Extracellular signal-regulated kinase 3 (ERK3) is a poorly characterized member of the mitogen-activated protein (MAP) kinase family. Functional analysis of the ERK3 signaling pathway has been hampered by a lack of knowledge about the substrates and downstream effectors of the kinase. Here, we used large-scale quantitative phosphoproteomics and targeted gene silencing to identify direct ERK3 substrates and gain insight into its cellular functions. Detailed validation of one candidate substrate i ...[more]