Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF-X
ORGANISM(S): Homo Sapiens (human) Mycobacterium Tuberculosis Mycobacterium Tuberculosis H37rv
SUBMITTER: Alexandre STELLA
LAB HEAD: Jerome Nigou
PROVIDER: PXD028477 | Pride | 2023-03-10
REPOSITORIES: pride
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F112397.dat | Other | |||
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Mosquera-Restrepo Sergio Fabián SF Zuberogoïtia Sophie S Gouxette Lucie L Layre Emilie E Gilleron Martine M Stella Alexandre A Rengel David D Burlet-Schiltz Odile O Caro Ana Cecilia AC Garcia Luis F LF Segura César C Peláez Jaramillo Carlos Alberto CA Rojas Mauricio M Nigou Jérôme J
Nature communications 20221214 1
An estimated one-third of tuberculosis (TB) cases go undiagnosed or unreported. Sputum samples, widely used for TB diagnosis, are inefficient at detecting infection in children and paucibacillary patients. Indeed, developing point-of-care biomarker-based diagnostics that are not sputum-based is a major priority for the WHO. Here, in a proof-of-concept study, we tested whether pulmonary TB can be detected by analyzing patient exhaled breath condensate (EBC) samples. We find that the presence of M ...[more]