Proteomics

Dataset Information

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Shotgun proteomics (qMS) of zinc-replete wild type and zinc-limited wild type, altRP operon deletion mutant and its complement strain in Mycolicibacterium (Mycobacterium) smegmatis

ABSTRACT: The study was designed to describe the effects of zinc limitation on gene expression in M. smegmatis by comparing the proteomes of zinc-replete and zinc-limited wild type. Additionally, the study informs how loss of the altRP operon impacts the proteome during zinc limitation by comparing the proteomes of zinc-limited ΔaltRP mutant to the zinc-replete and zinc-limited wild type, and to confirm which changes are complemented in the complement strain (ΔaltRP/c).

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mycobacterium Smegmatis (strain Atcc 700084 / Mc(2)155)

SUBMITTER: Allexa Dow  

LAB HEAD: Sladjana Prisic

PROVIDER: PXD029588 | Pride | 2021-11-10

REPOSITORIES: Pride

Json Xml

Dataset's files

Source:
Action DRS
Msm_X_SpCs_ALL.csv Csv
QEPlus2_12082017_WT_ZLM1.raw Raw
QEPlus2_12082017_WT_ZLM2.raw Raw
QEPlus2_12082017_WT_ZLM3.raw Raw
QEPlus2_12082017_WT_ZRM1.raw Raw
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Publications

Clinical significance of Matrilin-3 gene polymorphism in Egyptian patients with primary knee osteoarthritis.

Diab Safia M SM   Kamal Howyda M HM   Mansour Amira I AI   Fawzy Rasha M RM   Azab Basma S BS  

European journal of rheumatology 20170704 3

<h4>Objective</h4>Osteoarthritis (OA) is a multifactorial, degenerative, and inflammatory disorder of joints causing damage of the articular cartilage, formation of osteophytes, and eburination of the subchondral bone. Matrilin-3 <i>(MATN-3)</i> is a non-collagenous oligomeric extracellular matrix protein (ECM), which is the smallest member of the matrilin family. This study was conducted to identify the potential association and clinical significance of <i>MATN-3</i> rs8176070 (SNP6) polymorphi  ...[more]