Proteomics

Dataset Information

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Duck liver LC-MSMS provides insights into trimethylamine metabolism


ABSTRACT: We aim to study the unusual TMA metabolism mechanism of ducks, and further explore the hidden reasons that led to the weakening TMA metabolism ability.To achieve this, transcriptome, proteome, and metagenome analyses were integrated based on the constructed duck populations with high TMA metabolism ability and low TMA metabolism ability.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Anas Platyrhynchos

TISSUE(S): Liver

SUBMITTER: Xingzheng Li  

LAB HEAD: Jiangxia Zheng

PROVIDER: PXD030109 | Pride | 2023-03-10

REPOSITORIES: Pride

Dataset's files

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Action DRS
181994-01_1.raw Raw
181994-01_10.raw Raw
181994-01_11.raw Raw
181994-01_12.raw Raw
181994-01_13.raw Raw
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Publications

FMO3 deficiency of duck leads to decreased lipid deposition and increased antibacterial activity.

Li Xingzheng X   Song Jianlou J   Shi Xuefeng X   Huang Mingyi M   Liu Lei L   Yi Guoqiang G   Yang Ning N   Xu Guiyun G   Zheng Jiangxia J  

Journal of animal science and biotechnology 20221116 1


<h4>Background</h4>Most duck eggs possess a fishy odor, indicating that ducks generally exhibit impaired trimethylamine (TMA) metabolism. TMA accumulation is responsible for this unpleasant odor, and TMA metabolism plays an essential role in trimethylaminuria (TMAU), also known as fish odor syndrome. In this study, we focused on the unusual TMA metabolism mechanism in ducks, and further explored the unclear reasons leading to the debilitating TMA metabolism.<h4>Methods</h4>To achieve this, trans  ...[more]

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