Proteomics

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The effect of dietary Spirulina microalga on the intestinal function of the post-weaned piglet


ABSTRACT: The aim of this study was to characterize the metabolomic and proteomic changes in the intestinal tissue of weaned piglets fed with diets containing Spirulina as an ingredient (10% incorporation in the diet), combining such information with histomorphology data.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Intestine

SUBMITTER: Josipa Kuleš  

LAB HEAD: Vladimir Mrljak

PROVIDER: PXD030446 | Pride | 2022-09-20

REPOSITORIES: Pride

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Publications

Effect of dietary Spirulina (Arthrospira platensis) on the intestinal function of post-weaned piglet: An approach combining proteomics, metabolomics and histological studies.

Martins Cátia F CF   Ribeiro David M DM   Matzapetakis Manolis M   Pinho Mário A MA   Kuleš Josipa J   Horvatić Anita A   Guillemin Nicolas N   Eckersall Peter David PD   Freire João P B JPB   de Almeida André M AM   Prates José A M JAM  

Journal of proteomics 20220910


The effect of dietary Spirulina (Arthrospira platensis) and CAZyme supplementation was assessed on the gut of weaned piglets, using an integrated NMR-metabolomics approach combined with Tandem Mass Tag labelled proteomics. Thirty weaned male piglets were assigned to one of the three following diets (n = 10): cereal and soybean meal basal diet (Control), basal diet with 10% Spirulina inclusion (SP) and SP diet supplemented with 0.01% lysozyme (SP + L). The experiment lasted 4 weeks and, upon slau  ...[more]

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