Dataset Information

Aging-Associated Changes in CSF Protein Abundances and Structures Revealed by a Modified LiP-MS Screen

ABSTRACT: We performed LiP-MS on CSF from young and old mice with a modified analysis pipeline. We found 38 protein groups that change in abundance with aging, most dominantly immunoglobulins of the IgM subclass. We discovered six high-confidence candidates that appeared to change in structure with aging.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cerebrospinal Fluid

SUBMITTER: Steven Shuken

LAB HEAD: Tony Wyss-Coray

PROVIDER: PXD031174 | Pride | 2022-08-22

REPOSITORIES: Pride

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			Action	DRS
	20200210_SShuken_WyssCoray_11036_C1C.raw	Raw
	20200210_SShuken_WyssCoray_11036_C1P.raw	Raw
	20200210_SShuken_WyssCoray_11036_C2C.raw	Raw
	20200210_SShuken_WyssCoray_11036_C2P.raw	Raw
	20200210_SShuken_WyssCoray_11036_C3C.raw	Raw

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Aging-Associated Changes in CSF Protein Abundances and Structures Revealed by a Modified LiP-MS Screen

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