Proteomics

Dataset Information

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Rattus norvegicus lung LC-MS/MS


ABSTRACT: Male Sprague-Dawley rats were used to establish exhausted-exercise model by motorized rodent treadmill. Yu-Ping-Feng-San at doses of 2.18 g/kg was administrated by gavage before exercise training for 10 consecutive days. Quantitative proteomics was performed for assessing the related mechanism of Yu-Ping-Feng-San.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Rattus Norvegicus (rat)

TISSUE(S): Lung

SUBMITTER: Di Wang  

LAB HEAD: Jing-Yan Han

PROVIDER: PXD032737 | Pride | 2022-08-12

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
190802-01_1-1.raw Raw
190802-01_1-10.raw Raw
190802-01_1-11.raw Raw
190802-01_1-12.raw Raw
190802-01_1-13.raw Raw
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Publications

Yu-Ping-Feng Formula Ameliorates Alveolar-Capillary Barrier Injury Induced by Exhausted-Exercise <i>via</i> Regulation of Cytoskeleton.

Wang Di D   Li Quan Q   Pan Chun-Shui CS   Yan Li L   Sun Kai K   Wang Xiao-Yi XY   Anwaier Gulinigaer G   Liao Qian-Zan QZ   Xie Ting-Ting TT   Fan Jing-Yu JY   Huo Xin-Mei XM   Wang Yuan Y   Han Jing-Yan JY  

Frontiers in pharmacology 20220624


<b>Background:</b> Yu-ping-feng powder (YPF) is a compound traditional Chinese medicine extensively used in China for respiratory diseases. However, the role of YPF in alveolar-capillary barrier dysfunction remains unknown. This study aimed to explore the effect and potential mechanism of YPF on alveolar-capillary barrier injury induced by exhausted exercise. <b>Methods:</b> Male Sprague-Dawley rats were used to establish an exhausted-exercise model by using a motorized rodent treadmill. YPF at  ...[more]

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