Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Oryza Sativa (rice)
TISSUE(S): Leaf
SUBMITTER: Li-Ning Lu
LAB HEAD: Lining Lu
PROVIDER: PXD032822 | Pride | 2022-10-15
REPOSITORIES: pride
Action | DRS | |||
---|---|---|---|---|
19-076_LLN0329_Lu-1.msf | Msf | |||
19-076_LLN0329_Lu-1.mzML | Mzml | |||
19-076_LLN0329_Lu-1.mzid.gz | Mzid | |||
19-076_LLN0329_Lu-1.raw | Raw | |||
19-076_LLN0329_Lu-2.msf | Msf |
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Nature communications 20220809 1
Linear (Met1-linked) ubiquitination is involved inflammatory and innate immune signaling. Previous studies have characterized enzymes regulating the addition and removal of this modification in mammalian systems. However, only a few plant-derived deubiquitinases targeting Met1-linked ubiquitin chains have been reported and their mechanism of action remains elusive. Here, using a dehydroalanine-bearing Met1-diubiquitin suicide probe, we discover OTUB1 from Oryza sativa (OsOTUB1) as a Met1-linked ...[more]