Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human) Chlorocebus Sabaeus
TISSUE(S): Lung, Epithelial Cell, Kidney
DISEASE(S): Covid-19
SUBMITTER: Tomer Yaron
LAB HEAD: Lewis C. Cantley
PROVIDER: PXD033015 | Pride | 2023-03-11
REPOSITORIES: Pride
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Science signaling 20221025 757
Multiple coronaviruses have emerged independently in the past 20 years that cause lethal human diseases. Although vaccine development targeting these viruses has been accelerated substantially, there remain patients requiring treatment who cannot be vaccinated or who experience breakthrough infections. Understanding the common host factors necessary for the life cycles of coronaviruses may reveal conserved therapeutic targets. Here, we used the known substrate specificities of mammalian protein ...[more]