Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Embryonic Stem Cell
SUBMITTER: Kristyna Pimkova
LAB HEAD: Kristyna Pimkova
PROVIDER: PXD033115 | Pride | 2022-06-09
REPOSITORIES: Pride
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KP127_H2O2_E_4ul_01.raw | Raw | |||
KP127_H2O2_Full_4ul_01.raw | Raw | |||
KP134_Rep2_E_6ul_01.raw | Raw | |||
KP134_Rep2_FT_2ul_01.raw | Raw | |||
KP134_Rep3_E_6ul_01.raw | Raw |
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Redox biology 20220523
Fetal and adult hematopoietic stem and progenitor cells (HSPCs) are characterized by distinct redox homeostasis that may influence their differential cellular behavior in normal and malignant hematopoiesis. In this work, we have applied a quantitative mass spectrometry-based redox proteomic approach to comprehensively describe reversible cysteine modifications in primary mouse fetal and adult HSPCs. We defined the redox state of 4,438 cysteines in fetal and adult HSPCs and demonstrated a higher ...[more]