Dataset Information
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of P. aeruginosa
Ontology highlight
ABSTRACT:
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Pseudomonas Aeruginosa (strain Ucbpp-pa14)
SUBMITTER: 
Byoung-Kyu Cho
LAB HEAD: Bruce Stanton
PROVIDER: PXD033165 | Pride | 2023-10-24
REPOSITORIES: Pride
Dataset's files
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Publications
An rRNA fragment in extracellular vesicles secreted by human airway epithelial cells increases the fluoroquinolone sensitivity of <i>P. aeruginosa</i>.
American journal of physiology. Lung cellular and molecular physiology 20230531 1
Lung infections caused by antibiotic-resistant strains of <i>Pseudomonas aeruginosa</i> are difficult to eradicate in immunocompromised hosts such as those with cystic fibrosis. We previously demonstrated that extracellular vesicles (EVs) secreted by primary human airway epithelial cells (AECs) deliver microRNA let-7b-5p to <i>P. aeruginosa</i> to suppress biofilm formation and increase sensitivity to beta-lactam antibiotics. In this study, we show that EVs secreted by AECs transfer multiple dis ...[more]
