Global proteomic analysis in Cryptococcus neoformans
Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Cryptococcus Neoformans H99-vivo
SUBMITTER: 
Ann-Yae Na
LAB HEAD: Sangkyu lee
PROVIDER: PXD033626 | Pride | 2024-05-23
REPOSITORIES: Pride
Dataset's files
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Publications
Casein kinase 2 complex: a central regulator of multiple pathobiological signaling pathways in <i>Cryptococcus neoformans</i>.
Choi Yeseul Y Yu Seong-Ryong S-R Lee Yujin Y Na Ann-Yae A-Y Lee Sangkyu S Heitman Joseph J Seo Ran R Lee Han-Seung H-S Lee Jong-Seung J-S Bahn Yong-Sun Y-S
mBio 20240109 2
The casein kinase 2 (CK2) complex has garnered extensive attention over the past decades as a potential therapeutic target for diverse human diseases, including cancer, diabetes, and obesity, due to its pivotal roles in eukaryotic growth, differentiation, and metabolic homeostasis. While CK2 is also considered a promising antifungal target, its role in fungal pathogens remains unexplored. In this study, we investigated the functions and regulatory mechanisms of the CK2 complex in <i>Cryptococcus ...[more]
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