Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Plasma
DISEASE(S): Type 1 Diabetes Mellitus
SUBMITTER: Maria Karoliina Hirvonen
LAB HEAD: Riitta Lahesmaa
PROVIDER: PXD033744 | Pride | 2023-09-26
REPOSITORIES: pride
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151005StenoDIPP_15E.raw | Raw | |||
151005StenoDIPP_15G.raw | Raw | |||
151005StenoDIPP_15H.raw | Raw | |||
151005StenoDIPP_15L.raw | Raw | |||
151006StenoDIPP_15A.raw | Raw |
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Scientific reports 20230924 1
Better understanding of the early events in the development of type 1 diabetes is needed to improve prediction and monitoring of the disease progression during the substantially heterogeneous presymptomatic period of the beta cell damaging process. To address this concern, we used mass spectrometry-based proteomics to analyse longitudinal pre-onset plasma sample series from children positive for multiple islet autoantibodies who had rapidly progressed to type 1 diabetes before 4 years of age (n ...[more]