Proteomics

Dataset Information

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Plasma proteomics reveals gilthead sea bream (Sparus aurata) impairment evoked by Sparicotyle chrysophrii


ABSTRACT: Sparicotylosis is an endemic parasitic disease across the Mediterranean Sea caused by the polyopisthocotylean monogenean Sparycotyle chrysophrii, which affects the gills of gilthead sea bream (Sparus aurata). Current disease-management, mitigation and treatment strategies are scarce against sparicotylosis. In order to successfully develop more efficient therapeutic strategies against this disease, understanding which molecular mechanisms and metabolic pathways are altered in the host is critical. This study aims to elucidate how S. chrysophrii infection modulates giltheadd seea bream physiological status and to identify the main altered biological processes through plasma proteomics of the host.

INSTRUMENT(S): TripleTOF 6600

ORGANISM(S): Sparus Aurata

TISSUE(S): Blood Plasma

DISEASE(S): Parasitic Infectious Disease

SUBMITTER: Luz Valero  

LAB HEAD: Ariadna Sitjà-Bobadilla

PROVIDER: PXD034541 | Pride | 2022-10-14

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
AS-210517_5.1.wiff Wiff
AS-210517_5.1.wiff.scan Wiff
AS-210517_5.2.wiff Wiff
AS-210517_5.2.wiff.scan Wiff
AS-210517_5.3.wiff Wiff
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Publications

A bloody interaction: plasma proteomics reveals gilthead sea bream (Sparus aurata) impairment caused by Sparicotyle chrysophrii.

Riera-Ferrer Enrique E   Piazzon M Carla MC   Del Pozo Raquel R   Palenzuela Oswaldo O   Estensoro Itziar I   Sitjà-Bobadilla Ariadna A  

Parasites & vectors 20220910 1


<h4>Background</h4>Sparicotylosis is an enzootic parasitic disease that is well established across the Mediterranean Sea. It is caused by the polyopisthocotylean monogenean Sparicotyle chrysophrii and affects the gills of gilthead sea bream (GSB; Sparus aurata). Current disease management, mitigation and treatment strategies are limited against sparicotylosis. To successfully develop more efficient therapeutic strategies against this disease, understanding which molecular mechanisms and metaboli  ...[more]

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