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Complexome profiling of testis tissue in WT and ClpP-/- mice

ABSTRACT: Mutations in the gene for the mitochondrial matrix protease CLPP can cause human Perrault syndrome, which is characterized by male and female infertility, progressive sensorineural deafness, ataxia and leukoencephalopathy. This gene encodes a peptidase that is conserved since bacteria and localizes to mitochondrial matrix in eukaryotes. To assess the assembly and stability of mitochondrial complexes testes of WT and ClpP-/- mice were dissected and enriched mitochondrial fraction was used for complexome profiling.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Testis

SUBMITTER: Jana Key

LAB HEAD: Georg Auburger

PROVIDER: PXD035352 | Pride | 2024-01-17

REPOSITORIES: Pride

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			Action	DRS
	Data_Analysis.xlsx	Xlsx
	Gel.jpg	Other
	P21_070_Heike_MouseTestis_KO_01.raw	Raw
	P21_070_Heike_MouseTestis_KO_02.raw	Raw
	P21_070_Heike_MouseTestis_KO_03.raw	Raw

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