Dataset Information

Proteomics,N-glycoproteomics and Phosphoproteomics of SARS-Cov-2 Infected Calu-3 Cells

ABSTRACT: We present an multiple proteomics study of SARS-Cov-2 infection to comprehensively decipher the changes in host cells in response to viral infection, including global proteomics, N-glycoproteomics and phosphoproteomics.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

SUBMITTER: Rui Chen

LAB HEAD: Rui Chen

PROVIDER: PXD037097 | Pride | 2024-01-26

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	Calu3_N-glycoproteome.zip	Other
	Calu3_phosphoproteome.zip	Other
	Calu3_total_proteome.zip	Other
	MaxQuant_1.5.2.8.zip	Other
	Y211006P00132R19348S01.raw	Raw

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Publications

Integrated Immunopeptidomics and Proteomics Study of SARS-CoV-2-Infected Calu-3 Cells Reveals Dynamic Changes in Allele-specific HLA Abundance and Antigen Presentation.

Chen Rui R Fulton Kelly M KM Tran Anh A Duque Diana D Kovalchik Kevin K Caron Etienne E Twine Susan M SM Li Jianjun J

Molecular & cellular proteomics : MCP 20230913 10

We present an integrated immunopeptidomics and proteomics study of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection to comprehensively decipher the changes in host cells in response to viral infection. Immunopeptidomics analysis identified viral antigens presented by host cells through both class I and class II MHC system for recognition by the adaptive immune system. The host proteome changes were characterized by quantitative proteomics and glycoproteomics and from these ...[more]

PMID: 37709257

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