Proteomics

Dataset Information

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Lung Adenocarcinoma (A549) Immunopeptidomics


ABSTRACT: Alterations in cellular antigen processing and presenting machinery has gained increased interest as a hallmark of cancer-related inflammation. Growing evidence suggest that proteasome composition and immunoproteasome expression can influence antigen processing. By performing immunopeptidomics on A549 lung adenocarcinoma cell line following depletion of proteasome regulator PSME4 we identified alterations in the antigenic landscape resulting from changes in proteasome processing.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Lung Cancer

SUBMITTER: Aaron Javitt  

LAB HEAD: Yifat Merbl

PROVIDER: PXD037365 | Pride | 2023-03-30

REPOSITORIES: pride

Dataset's files

Source:
Action DRS
EX480YM_072_4919_14092022.raw Raw
EX480YM_072_4920_14092022.raw Raw
EX480YM_072_4921_14092022.raw Raw
EX480YM_072_4922_14092022.raw Raw
EX480YM_072_4923_14092022.raw Raw
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