Dataset Information

Herpes Simplex Virus 1 (HSV-1) Infected Cell Protein 0 (ICP0) Targets of Ubiquitination during Productive Infection in Primary Adult Sensory Neurons

ABSTRACT: Identify neuron-specific ubiquitin targets of Infected Cell Protein 0 (ICP0) in adult sensory neurons.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain, Dorsal Root Ganglion

DISEASE(S): Herpes Simplex

SUBMITTER: Keith Ray

LAB HEAD: Andrea S. Bertke

PROVIDER: PXD037767 | Pride | 2023-03-11

REPOSITORIES: pride

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Dataset's files

Source:

			Action	DRS
	MSB41825Band_01-_3_.msf	Msf
	MSB41825Band_01-_3_.msfView	Msf
	MSB41825Band_01-_3_.mzML	Mzml
	MSB41825Band_01-_3_.mzid.gz	Mzid
	MSB41825Band_01-_3_.pdResult	Other

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Herpes Simplex Virus 1 (HSV-1) Infected Cell Protein 0 (ICP0) Targets of Ubiquitination during Productive Infection of Primary Adult Sensory Neurons.

Harrell Telvin L TL Davido David J DJ Bertke Andrea S AS

International journal of molecular sciences 20230202 3

Herpes simplex virus 1 (HSV-1) enters sensory neurons with the potential for productive or latent infection. For either outcome, HSV-1 must curtail the intrinsic immune response, regulate viral gene expression, and remove host proteins that could restrict viral processes. Infected cell protein 0 (ICP0), a virus-encoded E3 ubiquitin ligase, supports these processes by mediating the transfer of ubiquitin to target proteins to change their location, alter their function, or induce their degradation ...[more]

PMID: 36769256

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