Immunopeptidomics of malignant mesothelioma to identify target antigens for T cell Immunotherapy
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ABSTRACT: Immunoaffinity purification was performed on human mesothelioma cell lines NCI-H2452, NCI-H28, MSTO-211H and JL1, on murine mesothelioma cell line AB12, as well as on mesothelioma samples from two patients (including tumor and benign tissues). Thereafter Immunopeptidomics by Mass Spectrometry on a Tims TOF Pro revealed the MHC peptide landscape of mesothelioma.
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)
TISSUE(S): Pleural Mesothelium, Mesothelium
DISEASE(S): Benign Mesothelioma,Malignant Mesothelioma
SUBMITTER: Rui Branca
LAB HEAD: Janne Lehtiö
PROVIDER: PXD038273 | Pride | 2023-09-08
REPOSITORIES: Pride
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