Proteomics

Dataset Information

0

PerTurboID of Plasmofium falciparum cytoadhesion complex


ABSTRACT: In this project proximity labeling was used to first identify proteins in the close vicinity of the P. falciparum exported kinase FIKK4.1 by fusing it to a biotin ligase. A conditional KO of the exported kinase FIKK4.1 was then generated for two identified targets, PTP4 and Kahrp in a FIKK4.1 conditional KO line. We then measured the proximity proteome of KAHRP and PTPT4 in the presence, and absence of FIKK4.1.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human) Plasmodium Falciparum Nf54

TISSUE(S): Erythrocyte, Blood

DISEASE(S): Malaria

SUBMITTER: Moritz Treeck  

LAB HEAD: Moritz Treeck

PROVIDER: PXD039125 | Pride | 2023-09-21

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
FIKK4.1_TurboID_raw.zip Other
FIKK4.1_turboID.zip Other
PerturboID_RAW.zip Other
PerturboID_txt.zip Other
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