Proteomics

Dataset Information

0

Quantitative proteomic study of total protein TMT labeling in 18 pig liver samples


ABSTRACT: Based on the work flow of quantitative proteomic analysis combined with TMT labeling and liquid chromatography-tandem mass spectrometry (LC-MS/MS), this study carried out quantitative proteomic analysis on the liver tissues of Tibetan pigs and Yorkshire pigs in Shannan (about 4000 m), Linzhi (about 3000 m) and Jiuzhaigou (about 1500 m), and compared the differences of protein mass spectra between the liver of living pigs at three altitudes.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Sus Scrofa Domesticus (domestic Pig)

TISSUE(S): Liver

SUBMITTER: 新萍 常  

LAB HEAD: Fang Geng

PROVIDER: PXD039758 | Pride | 2023-03-11

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
TQ01.zip Other
TQ02.zip Other
TQ03.zip Other
WD290TQ01_Fr1.raw Raw
WD290TQ01_Fr2.raw Raw
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Publications

Quantitative Proteomic Analysis of Tibetan Pig Livers at Different Altitudes.

Gu Xuedong X   Chang Xinping X   Yang Lin L   Chamba Yangzom Y   Geng Fang F  

Molecules (Basel, Switzerland) 20230210 4


In this study, the differences in protein profiles between the livers of Shannan Tibetan pigs (SNT), Linzhi Tibetan pigs (LZT) and Jiuzhaigou Tibetan pigs (JZT) were comparatively analyzed by tandem mass spectrometry-labeling quantitative proteomics. A total of 6804 proteins were identified: 6471 were quantified and 1095 were screened as differentially expressed proteins (DEPs). Bioinformatics analysis results show that, compared with JZT livers, up-regulated DEPs in SNT and LZT livers mainly pr  ...[more]

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