Ontology highlight
ABSTRACT:
INSTRUMENT(S): ultraflex
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Josephine Wu
LAB HEAD: Gordana Vunjak-Novakovic
PROVIDER: PXD040232 | Pride | 2023-07-20
REPOSITORIES: Pride
Action | DRS | |||
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JW1166_RawFiles.zip | Other | |||
JW1166_timsTofPro_diaPASEF_SDB_SCXLib_ProteinGroupds_Corrected.xlsx | Xlsx |
Items per page: 5 1 - 2 of 2 |
Wu Josephine Y JY Yeager Keith K Tavakol Daniel Naveed DN Morsink Margaretha M Wang Bryan B Soni Rajesh Kumar RK Hung Clark T CT Vunjak-Novakovic Gordana G
Cell reports 20230512 5
In tissue development and homeostasis, transforming growth factor (TGF)-β signaling is finely coordinated by latent forms and matrix sequestration. Optogenetics can offer precise and dynamic control of cell signaling. We report the development of an optogenetic human induced pluripotent stem cell system for TGF-β signaling and demonstrate its utility in directing differentiation into the smooth muscle, tenogenic, and chondrogenic lineages. Light-activated TGF-β signaling resulted in expression o ...[more]