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Covid Human plasma LC-MS Multiplatform Analyses Reveal Distinct Drivers of Systemic Pathogenesis in Adult Versus Pediatric Severe Acute COVID-19

ABSTRACT: The adult data set. The pathogenesis of multi-organ dysfunction associated with severe acute SARS-CoV-2 infection remains poorly understood. Endothelial damage and microvascular thrombosis have been identified as drivers of COVID-19 severity, yet the mechanisms underlying these processes remain elusive. A multiomics approach identified alterations in analytes associated with fluid shear stress-responsive pathways in critically ill COVID-19 adults as compared to non-COVID critically ill adults.

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

SUBMITTER: Blaine Roberts

LAB HEAD: Blanie R. Roberts

PROVIDER: PXD040438 | Pride | 2023-03-06

REPOSITORIES: Pride

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			Action	DRS
	02COVID.raw	Raw
	03COVID.raw	Raw
	05COVID.raw	Raw
	06COVID.raw	Raw
	07COVID.raw	Raw

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