Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Eclipse, Q Exactive HF-X
ORGANISM(S): Homo Sapiens (human) Saccharomyces Cerevisiae (baker's Yeast) Saccharomyces Cerevisiae
TISSUE(S): T Cell
SUBMITTER: Moritz Madern
LAB HEAD: Markus Hartl
PROVIDER: PXD040449 | Pride | 2023-12-19
REPOSITORIES: Pride
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Molecular & cellular proteomics : MCP 20231212 1
Multiplex proteomics using isobaric labeling tags has emerged as a powerful tool for the simultaneous relative quantification of peptides and proteins across multiple experimental conditions. However, the quantitative accuracy of the approach is largely compromised by ion interference, a phenomenon that causes fold changes to appear compressed. The degree of compression is generally unknown, and the contributing factors are poorly understood. In this study, we thoroughly characterized ion interf ...[more]