Extracellular matrix derived from oral mesenchymal stem cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF-X
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Primary Cell
SUBMITTER: 
Vanessa Masson
LAB HEAD: Damarys Loew
PROVIDER: PXD040575 | Pride | 2024-05-24
REPOSITORIES: Pride
Publications
Human dental pulp stem cells derived extracellular matrix promotes mineralization via Hippo and Wnt pathways.
Kornsuthisopon Chatvadee C Nowwarote Nunthawan N Chansaenroj Ajjima A Photichailert Suphalak S Rochanavibhata Sunisa S Klincumhom Nuttha N Petit Stephane S Dingli Florent F Loew Damarys D Fournier Benjamin P J BPJ Osathanon Thanaphum T
Scientific reports 20240321 1
Extracellular matrix (ECM) is an intricate structure providing the microenvironment niche that influences stem cell differentiation. This study aimed to investigate the efficacy of decellularized ECM derived from human dental pulp stem cells (dECM_DPSCs) and gingival-derived mesenchymal stem cells (dECM_GSCs) as an inductive scaffold for osteogenic differentiation of GSCs. The proteomic analysis demonstrated that common and signature matrisome proteins from dECM_DPSCs and dECM_GSCs were related ...[more]
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