Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Corneal Epithelium
SUBMITTER: Prerana Wagle
LAB HEAD: Maria Notara
PROVIDER: PXD041004 | Pride | 2023-10-24
REPOSITORIES: Pride
Action | DRS | |||
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2629_PRIDE.zip | Other | |||
E2_ColID_257_2629_01.raw | Raw | |||
E2_ColID_257_2629_02.raw | Raw | |||
E2_ColID_257_2629_03.raw | Raw | |||
E2_ColID_257_2629_04.raw | Raw |
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Cells 20230627 13
The limbus, the vascularized junction between the cornea and conjunctiva, is thought to function as a barrier against corneal neovascularization. However, the exact mechanisms regulating this remain unknown. In this study, the limbal epithelial stem cell (LESC) marker ABCB5 was used to investigate the role of LESCs in corneal neovascularization. In an ABCB5KO model, a mild but significant increase of limbal lymphatic and blood vascular network complexity was observed in developing mice (4 weeks) ...[more]