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The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation

ABSTRACT: Our studies establish the unique properties of the cyclimids as versatile warheads in TPD and a systematic biochemical approach for quantifying ternary complex formation to predict their cellular degradation activity, which together will accelerate the development of novel CRBN-targeting bifunctional degraders.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): T Cell

SUBMITTER: Christina Woo

LAB HEAD: Christina Woo

PROVIDER: PXD041494 | Pride | 2024-01-26

REPOSITORIES: Pride

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			Action	DRS
	Cyclimid_globalproteomics.msf	Msf
	Cyclimid_globalproteomics_new.msf	Msf
	globalproteomics_Fr10.raw	Raw
	globalproteomics_Fr11.raw	Raw
	globalproteomics_Fr12.raw	Raw

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