Proteomics

Dataset Information

0

HNE-modification identification of ApoAI


ABSTRACT: In this research, two 4-hydroxy-2-nonenal modified peptides with differential performance were identified in the plasma of patients with coronary artery disease, whether their antibodies were different in the plasma of patients with coronary artery disease and healthy people.

INSTRUMENT(S): LTQ Orbitrap Elite

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): Cardiovascular System Disease

SUBMITTER: Claire Chang  

LAB HEAD: Ching-Yu Lin

PROVIDER: PXD041969 | Pride | 2024-07-03

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
AE-11_140403.raw Raw
AE-11_140403.xml Xml
AE-12_140403.raw Raw
AE-12_140403.xml Xml
AE-1_140403.raw Raw
Items per page:
1 - 5 of 18
altmetric image

Publications

Low Levels of IgM Recognizing 4-Hydroxy-2-Nonenal-Modified Apolipoprotein A-I Peptide and Its Association with the Severity of Coronary Artery Disease in Taiwanese Patients.

Lei Meng-Huan MH   Hsu Po-Wen PW   Tsai Yin-Tai YT   Chang Chen-Chi CC   Tsai I-Jung IJ   Hsu Hung H   Cheng Ming-Hui MH   Huang Ying-Li YL   Lin Hung-Tse HT   Hsu Yu-Cheng YC   Lin Ching-Yu CY  

Current issues in molecular biology 20240620 6


Autoantibodies against apolipoprotein A-I (ApoA-I) are associated with cardiovascular disease risks. We aimed to examine the 4-hydroxy-2-nonenal (HNE) modification of ApoA-I in coronary artery disease (CAD) and evaluate the potential risk of autoantibodies against their unmodified and HNE-modified peptides. We assessed plasma levels of ApoA-I, HNE-protein adducts, and autoantibodies against unmodified and HNE-peptide adducts, and significant correlations and odds ratios (ORs) were examined. Two  ...[more]

Similar Datasets

2014-02-27 | E-GEOD-53314 | biostudies-arrayexpress
2021-03-24 | PXD018549 | Pride
2006-03-10 | E-MEXP-564 | biostudies-arrayexpress
2009-06-30 | E-MEXP-2113 | biostudies-arrayexpress
2015-06-05 | E-GEOD-69587 | biostudies-arrayexpress
2018-10-04 | GSE120774 | GEO
2015-05-05 | GSE68506 | GEO
2015-06-05 | GSE69587 | GEO
| PRJNA91395 | ENA
2008-08-23 | GSE10938 | GEO