Dataset Information

CFdb: A harmonized resource of co-fractionation mass spectrometry data

ABSTRACT: A total of 411 co-fractionation mass spectrometry (CF-MS) experiments were downloaded from public proteomics repositories such as PRIDE and MassIVE, then re-analyzed with MaxQuant. This repository provides complete MaxQuant outputs from all 411 experiments.

INSTRUMENT(S): LTQ Orbitrap, LTQ Orbitrap Velos, LTQ, Q Exactive

ORGANISM(S): Rattus Norvegicus (rat) Caenorhabditis Elegans Oryza Sativa (rice) Xenopus Laevis (african Clawed Frog) Triticum Aestivum (wheat) Drosophila Melanogaster (fruit Fly) Homo Sapiens (human) Escherichia Coli Trypanosoma Brucei Arabidopsis Thaliana (mouse-ear Cress) Zea Mays (maize) Dictyostelium Discoideum (slime Mold) Mus Musculus (mouse)

SUBMITTER: Michael Skinnider

LAB HEAD: Leonard Foster

PROVIDER: PXD042664 | Pride | 2024-01-26

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	CFdb-files.csv.zip	Csv
	MaxQuant-outputs-phosphorylation.tar	Other
	MaxQuant-outputs.tar	Other

Items per page:

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Publications

Mapping protein states and interactions across the tree of life with co-fractionation mass spectrometry.

Skinnider Michael A MA Akinlaja Mopelola O MO Foster Leonard J LJ

Nature communications 20231215 1

We present CFdb, a harmonized resource of interaction proteomics data from 411 co-fractionation mass spectrometry (CF-MS) datasets spanning 21,703 fractions. Meta-analysis of this resource charts protein abundance, phosphorylation, and interactions throughout the tree of life, including a reference map of the human interactome. We show how large-scale CF-MS data can enhance analyses of individual CF-MS datasets, and exemplify this strategy by mapping the honey bee interactome. ...[more]

PMID: 38102123

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