Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Thoracic Aortic Aneurysm
SUBMITTER: Juan A Lopez
LAB HEAD: Juan A Lopez
PROVIDER: PXD043062 | Pride | 2024-10-17
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
JAL_Glo_TMT_Dec2020_Fr1.msf | Msf | |||
JAL_Glo_TMT_Dec2020_Fr1.raw | Raw | |||
JAL_Glo_TMT_Dec2020_Fr2.msf | Msf | |||
JAL_Glo_TMT_Dec2020_Fr2.raw | Raw | |||
JAL_Glo_TMT_Dec2020_Fr3.msf | Msf |
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Journal of proteome research 20240409 8
Thoracic aortic aneurysm (TAA) is mainly sporadic and with higher incidence in the presence of a bicuspid aortic valve (BAV) for unknown reasons. The lack of drug therapy to delay TAA progression lies in the limited knowledge of pathophysiology. We aimed to identify the molecular hallmarks that differentiate the aortic dilatation associated with BAV and tricuspid aortic valve (TAV). Aortic vascular smooth muscle cells (VSMCs) isolated from sporadic TAA patients with BAV or TAV were analyzed by m ...[more]